3-Chloro-4-methoxyaniline → HCID 18546375, compound

HRID 1267360Notes

Reaction equation

HRID 1267360 reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[Cl:12][C:13]1[CH:14]=[C:15]([CH:17]=[CH:18][C:19]=1[O:20][CH3:21])[NH2:16]>>[Cl:12][C:13]1[CH:14]=[C:15]([NH:16][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[CH2:8][C:9]([OH:11])=[O:10])[CH:17]=[CH:18][C:19]=1[O:20][CH3:21]

Participants

3

Procedure

In the manner described in example 3, 2-bromophenylacetic acid is condensed with 3-chloro-4-methoxyaniline to yield 2-[(3-chloro-4-methoxyphenyl)amino]phenylacetic acid.

Sources & evidence

ORD record
ord-d57703ac10d84cfaa7f8da5d1297391d
Source dataset
uspto-grants-2003_04
Patent number
US06552077B2

Reaction notes

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