6-Chloro-m-anisidine → 2-[(3-Methoxy-6-chlorophenyl)amino]phenylacetic acid

HRID 1267362Notes

Reaction equation

HRID 1267362 reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[CH3:12][O:13][C:14]1[CH:15]=[C:16]([C:18]([Cl:21])=[CH:19][CH:20]=1)[NH2:17]>>[CH3:12][O:13][C:14]1[CH:15]=[C:16]([NH:17][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[CH2:8][C:9]([OH:11])=[O:10])[C:18]([Cl:21])=[CH:19][CH:20]=1

Participants

3

Reactant 2

HCID 754606-Chloro-m-anisidineHCID 877542-Bromophenylacetic acid

Product 1

HCID 185464122-[(3-Methoxy-6-chlorophenyl)amino]phenylacetic acid

Procedure

In the manner described in example 3, 2-bromophenylacetic acid is condensed with 3-methoxy-6-chloroaniline to yield 2-[(3-methoxy-6-chlorophenyl)amino]phenylacetic acid.

Sources & evidence

ORD record
ord-e58412b80ba448cab6a4be5679db8895
Source dataset
uspto-grants-2003_04
Patent number
US06552077B2

Reaction notes

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