2-Bromophenylacetic acid → 2-[(2-Methoxy-3-fluorophenyl)amino]phenylacetic acid

HRID 1267363Notes

Reaction equation

HRID 1267363 reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[CH3:12][O:13][C:14]1[C:20]([F:21])=[CH:19][CH:18]=[CH:17][C:15]=1[NH2:16]>>[CH3:12][O:13][C:14]1[C:20]([F:21])=[CH:19][CH:18]=[CH:17][C:15]=1[NH:16][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10]

Participants

3

Reactant 2

HCID 877542-Bromophenylacetic acidHCID 5811093-Fluoro-2-methoxyaniline

Product 1

HCID 185463552-[(2-Methoxy-3-fluorophenyl)amino]phenylacetic acid

Procedure

In the manner described in example 3, 2-bromophenylacetic acid is condensed with 2-methoxy-3-fluoroaniline to yield 2-[(2-methoxy-3-fluorophenyl)amino]phenylacetic acid.

Sources & evidence

ORD record
ord-2422bc69a4d9421caa8e27e7a19dd97f
Source dataset
uspto-grants-2003_04
Patent number
US06552077B2

Reaction notes

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