2-Methoxy-5-nitroaniline → 2-[(2-Methoxy-5-nitrophenyl)amino]phenylacetic acid

HRID 1267366Notes

Reaction equation

HRID 1267366 reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[CH3:12][O:13][C:14]1[CH:20]=[CH:19][C:18]([N+:21]([O-:23])=[O:22])=[CH:17][C:15]=1[NH2:16]>>[CH3:12][O:13][C:14]1[CH:20]=[CH:19][C:18]([N+:21]([O-:23])=[O:22])=[CH:17][C:15]=1[NH:16][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10]

Participants

3

Reactant 2

HCID 74472-Methoxy-5-nitroanilineHCID 877542-Bromophenylacetic acid

Product 1

HCID 185463792-[(2-Methoxy-5-nitrophenyl)amino]phenylacetic acid

Procedure

In the manner described in example 3, 2-bromophenylacetic acid is condensed with 2-methoxy-5-nitroaniline to yield 2-[(2-methoxy-5-nitrophenyl)amino]phenylacetic acid.

Sources & evidence

ORD record
ord-686f9289ffe8490fb435dce140761a07
Source dataset
uspto-grants-2003_04
Patent number
US06552077B2

Reaction notes

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