2,5-Difluoroaniline → HCID 18546335, compound

HRID 1267387Notes

Reaction equation

HRID 1267387 reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[F:12][C:13]1[CH:19]=[CH:18][C:17]([F:20])=[CH:16][C:14]=1[NH2:15]>>[F:12][C:13]1[CH:19]=[CH:18][C:17]([F:20])=[CH:16][C:14]=1[NH:15][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10]

Participants

3

Reactant 2

HCID 677752,5-DifluoroanilineHCID 877542-Bromophenylacetic acid

Product 1

HCID 18546335HCID 18546335, compound

Procedure

In the manner described in example 3, 2-bromophenylacetic acid is condensed with 2,5-difluoroaniline to yield 2-[(2,5-difluorophenyl)amino]phenylacetic acid.

Sources & evidence

ORD record
ord-e4ed8e239e404434944d37d9a6e5dbf2
Source dataset
uspto-grants-2003_04
Patent number
US06552077B2

Reaction notes

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