2,3-Difluoroaniline → 2-[(2,3-Difluorophenyl)amino]phenylacetic acid

HRID 1267388Notes

Reaction equation

HRID 1267388 reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[F:12][C:13]1[C:19]([F:20])=[CH:18][CH:17]=[CH:16][C:14]=1[NH2:15]>>[F:12][C:13]1[C:19]([F:20])=[CH:18][CH:17]=[CH:16][C:14]=1[NH:15][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10]

Participants

3

Reactant 2

HCID 782782,3-DifluoroanilineHCID 877542-Bromophenylacetic acid

Product 1

HCID 185463732-[(2,3-Difluorophenyl)amino]phenylacetic acid

Procedure

In the manner described in example 3 2-bromophenylacetic acid is condensed with 2,3-difluoroaniline to yield 2-[(2,3-difluorophenyl)amino]phenylacetic acid.

Sources & evidence

ORD record
ord-842103680023439596b2d6b3a5e7a2fe
Source dataset
uspto-grants-2003_04
Patent number
US06552077B2

Reaction notes

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