3-Chloro-4-fluoroaniline → HCID 18546384, compound

HRID 1267392Notes

Reaction equation

HRID 1267392 reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[Cl:12][C:13]1[CH:14]=[C:15]([CH:17]=[CH:18][C:19]=1[F:20])[NH2:16]>>[Cl:12][C:13]1[CH:14]=[C:15]([NH:16][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[CH2:8][C:9]([OH:11])=[O:10])[CH:17]=[CH:18][C:19]=1[F:20]

Participants

3

Reactant 2

HCID 97083-Chloro-4-fluoroanilineHCID 877542-Bromophenylacetic acid

Product 1

HCID 18546384HCID 18546384, compound

Procedure

In the manner described in example 3, 2-bromophenylacetic acid is condensed with 3-chloro-4-fluoroaniline to yield 2-[(3-chloro-4-fluorophenyl)amino]phenylacetic acid.

Sources & evidence

ORD record
ord-7eff2a457d43472e8f457586f35265dc
Source dataset
uspto-grants-2003_04
Patent number
US06552077B2

Reaction notes

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