2-Bromophenylacetic acid → HCID 18546364, compound

HRID 1267393Notes

Reaction equation

HRID 1267393 reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[F:12][C:13]1[CH:19]=[C:18]([Cl:20])[CH:17]=[CH:16][C:14]=1[NH2:15]>>[F:12][C:13]1[CH:19]=[C:18]([Cl:20])[CH:17]=[CH:16][C:14]=1[NH:15][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10]

Participants

3

Reactant 2

HCID 877542-Bromophenylacetic acidHCID 938984-Chloro-2-fluoroaniline

Product 1

HCID 18546364HCID 18546364, compound

Procedure

In the manner described in example 3, 2-bromophenylacetic acid is condensed with 2-fluoro-4-chloroaniline to yield 2-[(2-fluoro-4-chlorophenyl)amino]phenylacetic acid.

Sources & evidence

ORD record
ord-68c6c60e03dd45ceb68f5339067e133b
Source dataset
uspto-grants-2003_04
Patent number
US06552077B2

Reaction notes

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