4-Chloro-3-nitroaniline → 2-[(3-Nitro-4-chlorophenyl)amino]phenylacetic acid

HRID 1267394Notes

Reaction equation

HRID 1267394 reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[N+:12]([C:15]1[CH:16]=[C:17]([CH:19]=[CH:20][C:21]=1[Cl:22])[NH2:18])([O-:14])=[O:13]>>[N+:12]([C:15]1[CH:16]=[C:17]([NH:18][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[CH2:8][C:9]([OH:11])=[O:10])[CH:19]=[CH:20][C:21]=1[Cl:22])([O-:14])=[O:13]

Participants

3

Reactant 2

HCID 124774-Chloro-3-nitroanilineHCID 877542-Bromophenylacetic acid

Product 1

HCID 185464162-[(3-Nitro-4-chlorophenyl)amino]phenylacetic acid

Procedure

In the manner described in example 3, 2-bromophenylacetic acid is condensed with 3-nitro-4-chloroaniline to yield 2-[(3-nitro-4-chlorophenyl)amino]phenylacetic acid.

Sources & evidence

ORD record
ord-ad6a030fcffc4f4d913bd62713252dc3
Source dataset
uspto-grants-2003_04
Patent number
US06552077B2

Reaction notes

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