3,4,5-Trichloroaniline → 2-[(3,4,5-Trichlorophenyl)amino]phenylacetic acid
Reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[Cl:12][C:13]1[CH:14]=[C:15]([CH:17]=[C:18]([Cl:21])[C:19]=1[Cl:20])[NH2:16]>>[Cl:12][C:13]1[CH:14]=[C:15]([NH:16][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[CH2:8][C:9]([OH:11])=[O:10])[CH:17]=[C:18]([Cl:21])[C:19]=1[Cl:20]Participants
3
Procedure
In the manner described in example 3, 2-bromophenylacetic acid is condensed with 3,4,5-trichloroaniline to yield 2-[(3,4,5-trichlorophenyl)amino]phenylacetic acid.
Sources & evidence
- ORD record
- ord-25925131c3494d24a8b721a6bd9d571c
- Source dataset
- uspto-grants-2003_04
- Patent number
- US06552077B2
Reaction notes
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