2-Bromophenylacetic acid → 2-[(2,4,5-Triflourophenyl)amino]phenylacetic acid

HRID 1267402Notes

Reaction equation

HRID 1267402 reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[F:12][C:13]1[CH:19]=[C:18]([F:20])[C:17]([F:21])=[CH:16][C:14]=1[NH2:15]>>[F:12][C:13]1[CH:19]=[C:18]([F:20])[C:17]([F:21])=[CH:16][C:14]=1[NH:15][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10]

Participants

3

Reactant 2

HCID 877542-Bromophenylacetic acidHCID 949532,4,5-Trifluoroaniline

Product 1

HCID 185463612-[(2,4,5-Triflourophenyl)amino]phenylacetic acid

Procedure

In the manner described in example 3, 2-bromophenylacetic acid is condensed with 2,4,5-triflouroaniline to yield 2-[(2,4,5-triflourophenyl)amino]phenylacetic acid.

Sources & evidence

ORD record
ord-ed4ae67603ca471cb17cde53b04017e3
Source dataset
uspto-grants-2003_04
Patent number
US06552077B2

Reaction notes

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