2-Bromophenylacetic acid → 2-[(2,3,4,6-Tetrafluorophenyl)amino]phenylacetic acid

HRID 1267403Notes

Reaction equation

HRID 1267403 reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[F:12][C:13]1[C:19]([F:20])=[C:18]([F:21])[CH:17]=[C:16]([F:22])[C:14]=1[NH2:15]>>[F:12][C:13]1[C:19]([F:20])=[C:18]([F:21])[CH:17]=[C:16]([F:22])[C:14]=1[NH:15][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10]

Participants

3

Reactant 2

HCID 877542-Bromophenylacetic acidHCID 1230482,3,4,6-Tetrafluoroaniline

Product 1

HCID 185463172-[(2,3,4,6-Tetrafluorophenyl)amino]phenylacetic acid

Procedure

In the manner described in example 3, 2-bromophenylacetic acid is condensed with 2,3,4,6-tetrafluoroaniline to yield 2-[(2,3,4,6-tetrafluorophenyl)amino]phenylacetic acid.

Sources & evidence

ORD record
ord-b81455b354b14ad09396e52081f5240d
Source dataset
uspto-grants-2003_04
Patent number
US06552077B2

Reaction notes

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