4-Propylaniline → 2-[(4-Propylphenyl)amino]phenylacetic acid
Reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[CH2:12]([C:15]1[CH:21]=[CH:20][C:18]([NH2:19])=[CH:17][CH:16]=1)[CH2:13][CH3:14]>>[CH2:12]([C:15]1[CH:21]=[CH:20][C:18]([NH:19][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[CH2:8][C:9]([OH:11])=[O:10])=[CH:17][CH:16]=1)[CH2:13][CH3:14]Participants
3
Procedure
In the manner described in example 3, 2-bromophenylacetic acid is condensed with 4-propylaniline to yield 2-[(4-propylphenyl)amino]phenylacetic acid.
Sources & evidence
- ORD record
- ord-d32130d27ee249c59f003c74d90fa37b
- Source dataset
- uspto-grants-2003_04
- Patent number
- US06552077B2
Reaction notes
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