反应详情

Starting with the allyl compound prepared in Example 8 and the ethyl 2-(5,5,6,6,7,7,8,8,8-nonafluorooctyl)-8-nonenoate prepared in Example 5, a procedure analogous to that as shown in Example 8 was repeated to give 10-[(3RS,4RS)-7-hydroxy-3-(4-hydroxyphenyl)-3-methylthiochroman-4-yl]-2-(5,5,6,6,7,7,8,8,8-nonafluorooctyl)decanoic acid.