Tetrahydrofuran → HCID 22650076, compound

Participants

Reaction Steps

A total of 15 mmole of acryloyl chloride was added dropwise to a mixture of 10 mmole of the above-prepared α, α-diethyl-1-adamantanemethanol, 20 mmole of triethylamine and 40 ml of tetrahydrofuran over about 30 minutes. After the completion of addition, the resulting mixture was stirred at room temperature for 6 hours. After the addition of water, the reaction mixture was concentrated, and the concentrate was subjected to column chromatography on a silica gel to thereby yield the title compound in a yield of 72%.

Provenance & Evidence