HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bohemine → HCID 11774448, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bohemine | HCID 2422 | — |
| Reactant | Bromine | HCID 24408 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 11774448 | HCID 11774448 | 90% |
Reaction Steps
1 mmol of 2-(3-hydroxypropylamino)-6-benzylamino-9-isopropylpurine was dissolved in chloroform and 1.1 mmol of bromine was added. The 8-bromo derivative hydrobromide was removed by filtration and crystallized from n-propanol-ether. M.p. 156-161° C. Yield 90%. TLC: chloroform-methanol (96:4), single spot. MS-ESI(+)m/z: 420, 422 [M+H]+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06552192B1 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-9e53c674c60c433c8f9338e326f440a6 |
| Source note | uspto-grants-2003_04 |