反应详情

Ethyl 3-(2,3,4-trimethoxyphenyl)propenoate (1.15 g) was dissolved in ethanol (20 mL), and to the solution 10% potassium hydroxide (1.21 g) was added, and the mixture was stirred at room temperature for 5 hours. The reaction mixture was concentrated under reduced pressure, water was added to the residue, and the mixture was adjusted to pH 2 with 2 M hydrochloric acid and extracted with ethyl acetate. The resultant organic layer was dried over anhydrous sodium sulfate and then concentrated under reduced pressure to obtain the title compound.

1. concentrationThe reaction mixture was concentrated under reduced pressure, water
2. additionwas added to the residue
3. extractionextracted with ethyl acetate
4. dry with materialThe resultant organic layer was dried over anhydrous sodium sulfate
5. concentrationconcentrated under reduced pressure