4-Fluorophenylboronic acid → HCID 18546823, compound

HRID 1267640Notes

Reaction equation

HRID 1267640 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5](B(O)O)=[CH:4][CH:3]=1.Cl[C:12]1[CH:13]=[C:14]([CH:20]=[CH:21][N:22]=1)[C:15]([O:17][CH2:18][CH3:19])=[O:16]>>[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:12]2[CH:13]=[C:14]([CH:20]=[CH:21][N:22]=2)[C:15]([O:17][CH2:18][CH3:19])=[O:16])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 2856454-Fluorophenylboronic acidHCID 2762942Ethyl 2-chloroisonicotinate

Product 1

HCID 18546823HCID 18546823, compound

Procedure

4-Fluorophenylboronic acid (166 mg) and ethyl 2-chloroisonicotinate (200 mg) were reacted in the same manner as in Preparation Example 1 to obtain the title compound.

Sources & evidence

ORD record
ord-d36959ebc2bd496ba8b2f6e8a78b4d7f
Source dataset
uspto-grants-2003_04
Patent number
US06552188B2

Reaction notes

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