4-(Trifluoromethyl)phenylboronic acid → HCID 18546854, compound

HRID 1267642Notes

Reaction equation

HRID 1267642 reaction equation
[F:1][C:2]([F:13])([F:12])[C:3]1[CH:8]=[CH:7][C:6](B(O)O)=[CH:5][CH:4]=1.Cl[C:15]1[CH:16]=[C:17]([CH:23]=[CH:24][N:25]=1)[C:18]([O:20][CH2:21][CH3:22])=[O:19]>>[F:1][C:2]([F:13])([F:12])[C:3]1[CH:8]=[CH:7][C:6]([C:15]2[CH:16]=[C:17]([CH:23]=[CH:24][N:25]=2)[C:18]([O:20][CH2:21][CH3:22])=[O:19])=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 27343894-(Trifluoromethyl)phenylboronic acidHCID 2762942Ethyl 2-chloroisonicotinate

Product 1

HCID 18546854HCID 18546854, compound

Procedure

4-Trifluoromethylphenylboronic acid (255 mg) and ethyl 2-chloroisonicotinate (200 mg) were reacted in the same manner as in Preparation Example 1 to obtain the title compound.

Sources & evidence

ORD record
ord-ac5b834ab5d648c6856b1cc6d8160c90
Source dataset
uspto-grants-2003_04
Patent number
US06552188B2

Reaction notes

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