4-Chloro-6-methylpyrimidine → HCID 18546794, compound

HRID 1267645Notes

Reaction equation

HRID 1267645 reaction equation
Cl[C:2]1[CH:7]=[C:6]([CH3:8])[N:5]=[CH:4][N:3]=1.[CH3:9][O:10][C:11]1[CH:12]=[C:13](B(O)O)[CH:14]=[C:15]([O:19][CH3:20])[C:16]=1[O:17][CH3:18]>>[CH3:8][C:6]1[CH:7]=[C:2]([C:13]2[CH:12]=[C:11]([O:10][CH3:9])[C:16]([O:17][CH3:18])=[C:15]([O:19][CH3:20])[CH:14]=2)[N:3]=[CH:4][N:5]=1

Participants

3

Reactant 2

HCID 5817964-Chloro-6-methylpyrimidineHCID 27343903,4,5-Trimethoxybenzeneboronic acid

Product 1

HCID 18546794HCID 18546794, compound

Procedure

4-Chloro-6-methylpyrimidine (913 mg) and 3,4,5-trimethoxyphenylboronic acid (2.73 g) were reacted in the same manner as in Preparation Example 1 to obtain the title compound.

Sources & evidence

ORD record
ord-7354c666bb0c45f699ae62a96e71e8c4
Source dataset
uspto-grants-2003_04
Patent number
US06552188B2

Reaction notes

Loading…