3,4,5-Trimethoxybenzaldehyde → 5-[(1E)-5-Bromo-1-penten-1-yl]-1,2,3-trimethoxybenzene

HRID 1267654Notes

Reaction equation

HRID 1267654 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:8]=[C:9]([O:13][CH3:14])[C:10]=1[O:11][CH3:12])[CH:6]=O.[Br-].[Br:16][CH2:17][CH2:18][CH2:19][CH2:20][P+](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1>>[Br:16][CH2:17][CH2:18][CH2:19]/[CH:20]=[CH:6]/[C:5]1[CH:4]=[C:3]([O:2][CH3:1])[C:10]([O:11][CH3:12])=[C:9]([O:13][CH3:14])[CH:8]=1

Participants

3

Reactant 2

HCID 68583,4,5-TrimethoxybenzaldehydeHCID 2733851(4-Bromobutyl)triphenylphosphanium bromide

Product 1

HCID 185468005-[(1E)-5-Bromo-1-penten-1-yl]-1,2,3-trimethoxybenzene

Procedure

3,4,5-Trimethoxybenzaldehyde (9.81 g) and 4-bromobutyltriphenylphosphonium bromide (23.93 g) were treated in the same manner as in Preparation Example 83 to obtain the title compound.

Sources & evidence

ORD record
ord-d9cec01fb43b46468c15e1769aaff365
Source dataset
uspto-grants-2003_04
Patent number
US06552188B2

Reaction notes

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