Hexahydro-1,4-diazepine → HCID 18546795, compound

HRID 1267655Notes

Reaction equation

HRID 1267655 reaction equation
Br[CH2:2][CH2:3][CH2:4]/[CH:5]=[CH:6]/[C:7]1[CH:12]=[C:11]([O:13][CH3:14])[C:10]([O:15][CH3:16])=[C:9]([O:17][CH3:18])[CH:8]=1.[NH:19]1[CH2:25][CH2:24][CH2:23][NH:22][CH2:21][CH2:20]1>>[CH3:18][O:17][C:9]1[CH:8]=[C:7](/[CH:6]=[CH:5]/[CH2:4][CH2:3][CH2:2][N:19]2[CH2:25][CH2:24][CH2:23][NH:22][CH2:21][CH2:20]2)[CH:12]=[C:11]([O:13][CH3:14])[C:10]=1[O:15][CH3:16]

Participants

3

Reactant 2

HCID 68163Hexahydro-1,4-diazepineHCID 185468005-[(1E)-5-Bromo-1-penten-1-yl]-1,2,3-trimethoxybenzene

Product 1

HCID 18546795HCID 18546795, compound

Procedure

(E)-5-Bromo-1-(3,4,5-trimethoxyphenyl)-1-pentene (434 mg) and homopiperazine (276 mg) were reacted in the same manner as in Preparation Example 4 to obtain the title compound.

Sources & evidence

ORD record
ord-f60ccb0092b9455a85cd92f66e27c989
Source dataset
uspto-grants-2003_04
Patent number
US06552188B2

Reaction notes

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