HRID1267666

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID84151

[1,1'-Biphenyl]-4-carbonyl chloride

C13H9ClO

结构：COc1cc(-c2cc(CN3CCNCC3)ccn2)cc(OC)c1OC

HCID12021155

未命名化合物

PRODUCTS

生成物

结构：COc1cc(-c2cc(CN3CCN(C(=O)c4ccc(-c5ccccc5)cc4)CC3)ccn2)cc(OC)c1OC

HCID18546798

N-(4-phenylbenzoyl)-N'-[[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl]piperazine

C32H33N3O4

PROCEDURE

实验过程

1-[[2-(3,4,5-Trimethoxyphenyl)pyridin-4-yl]methyl]-piperazine (103 mg) and 4-phenylbenzoyl chloride (45 mg) were reacted in the same manner as in Example 46 to obtain the title compound as a free base.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-246c0a51745a4a29bd78b30758155177
来源数据集: uspto-grants-2003_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06552188B2
来源说明: uspto-grants-2003_04

反应 SMILES

[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:13]2[CH:18]=[C:17]([CH2:19][N:20]3[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]3)[CH:16]=[CH:15][N:14]=2)[CH:6]=[C:7]([O:11][CH3:12])[C:8]=1[O:9][CH3:10].[C:26]1([C:32]2[CH:40]=[CH:39][C:35]([C:36](Cl)=[O:37])=[CH:34][CH:33]=2)[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1>>[C:26]1([C:32]2[CH:33]=[CH:34][C:35]([C:36]([N:23]3[CH2:24][CH2:25][N:20]([CH2:19][C:17]4[CH:16]=[CH:15][N:14]=[C:13]([C:5]5[CH:6]=[C:7]([O:11][CH3:12])[C:8]([O:9][CH3:10])=[C:3]([O:2][CH3:1])[CH:4]=5)[CH:18]=4)[CH2:21][CH2:22]3)=[O:37])=[CH:39][CH:40]=2)[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=1