HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Phenylprop-2-enoyl chloride → N-cinnamoyl-N'-[[2-(3,4,5-trimethoxyphenyl)-pyridin-4-yl]methyl]piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Phenylprop-2-enoyl chloride | HCID 66023 | — |
| Reactant | 1-[[2-(3,4,5-Trimethoxyphenyl)pyridin-4-yl]-methyl]piperazine | HCID 12021155 | — |
| Product | N-cinnamoyl-N'-[[2-(3,4,5-trimethoxyphenyl)-pyridin-4-yl]methyl]piperazine | HCID 69181767 | — |
Reaction Steps
1-[[2-(3,4,5-Trimethoxyphenyl)pyridin-4-yl]methyl]-piperazine (103 mg) and cinnamoyl chloride (65 mg) were reacted in the same manner as in Example 46 to obtain the title compound as a free base.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06552188B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-6c934ba88cbc4b2fbc273b40f84d74e8 |
| Source note | uspto-grants-2003_04 |