HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-Carbamoyl-imidazo-[1,2-a]-quinoxaline-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | Ethyl 4-carbamoyl-imidazo-[1,2-a]-quinoxaline-2-carboxylate | HCID 14067521 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | 4-Carbamoyl-imidazo-[1,2-a]-quinoxaline-2-carboxylic acid | HCID 14067522 | 98.6% |
Reaction Steps
A suspension of 0.315 g of the product of Step B, 35 ml of water, 12 ml of ethanol and 6 ml of 1 N sodium hydroxide was stirred overnight to obtain a suspension of the white sodium salt which was acidified with concentrated hydrochloric acid. The mixture was filtered to obtain 0.28 g of 4-carbamoyl-imidazo-[1,2-a]-quinoxaline-2-carboxylic acid in the form of a buff crystalline solid melting at 298°-300° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04254123 |
| Source dataset | uspto-grants-1981_03 |
| ORD ID | ord-18f30057d9944392968299950e96f77e |
| Source note | uspto-grants-1981_03 |