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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1267761Generated: October 25, 2026

Ethyl 2-(4,4,5,5,5-pentafluoropentyl)-8-nonenoate → 10-[(3RS,4RS)-3-ethyl-7-hydroxy-3-(4-hydroxyphenyl)thiochroman-4-yl]-2-(4,4,5,5,5-pentafluoropentyl)decanoic acid

https://huagongshe.com/reaction/1267761

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-(4,4,5,5,5-pentafluoropentyl)-8-nonenoateHCID 12043782—
Reactant10-[(3RS,4RS)-3-ethyl-7-hydroxy-3-(4-hydroxyphenyl)thiochroman-4-yl]-2-(7,7,8,8,8-pentafluoro-octyl)decanoic acidHCID 18546277—
Product10-[(3RS,4RS)-3-ethyl-7-hydroxy-3-(4-hydroxyphenyl)thiochroman-4-yl]-2-(4,4,5,5,5-pentafluoropentyl)decanoic acidHCID 9938922—

Reaction Steps

Starting with the allyl compound prepared in Example 13 and the ethyl 2-(4,4,5,5,5-pentafluoropentyl)-8-nonenoate prepared in Example 10, the same procedure as shown in Example 13 was repeated to give 10-[(3RS,4RS)-3-ethyl-7-hydroxy-3-(4-hydroxyphenyl)thiochroman-4-yl]-2-(4,4,5,5,5-pentafluoropentyl)decanoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06552068B1
Source datasetuspto-grants-2003_04
ORD IDord-7630dab423ed4346bf19c0b7f4e43aaf
Source noteuspto-grants-2003_04