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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1267772Generated: October 25, 2026

Ethyl 2-(5,5,6,6,6-pentafluorohexyl)-9-decenoate → 11-[(3RS,4RS)-3-ethyl-7-hydroxy-3-(4-hydroxyphenyl)chroman-4-yl]-2-(5,5,6,6,6-pentafluorohexyl)undecanoic acid

https://huagongshe.com/reaction/1267772

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-(5,5,6,6,6-pentafluorohexyl)-9-decenoateHCID 18546254—
Reactant11-[(3RS,4RS)-3-ethyl-7-hydroxy-3-(4-hydroxyphenyl)chroman-4-yl]-2-(7,7,8,8,8-pentafluorooctyl)-undecanoic acidHCID 18546264—
Product11-[(3RS,4RS)-3-ethyl-7-hydroxy-3-(4-hydroxyphenyl)chroman-4-yl]-2-(5,5,6,6,6-pentafluorohexyl)undecanoic acidHCID 18546283—

Reaction Steps

Starting with the allyl compound prepared in Example 21 and the ethyl 2-(5,5,6,6,6-pentafluorohexyl)-9-decenoate prepared in Example 5, the same procedure as shown in Example 21 was repeated to give 11-[(3RS,4RS)-3-ethyl-7-hydroxy-3-(4-hydroxyphenyl)chroman-4-yl]-2-(5,5,6,6,6-pentafluorohexyl)undecanoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06552068B1
Source datasetuspto-grants-2003_04
ORD IDord-08f71b0a0b96448db5d89fd203b65fd9
Source noteuspto-grants-2003_04