HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-(4,4,5,5,5-pentafluoropentyl)-9-decenoate → 11-[(3RS,4RS)-7-hydroxy-3-(4-hydroxyphenyl)-3-propylchroman-4-yl]-2-(4,4,5,5,5-pentafluoropentyl)undecanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-(4,4,5,5,5-pentafluoropentyl)-9-decenoate | HCID 12043786 | — |
| Reactant | (3RS,4RS)-7-methoxymethoxy-3-(4-methoxymethoxyphenyl)-4-(2-propenyl)-3-propylchroman | HCID 18546265 | — |
| Product | 11-[(3RS,4RS)-7-hydroxy-3-(4-hydroxyphenyl)-3-propylchroman-4-yl]-2-(4,4,5,5,5-pentafluoropentyl)undecanoic acid | HCID 10211366 | — |
Reaction Steps
Starting with (3RS,4RS)-7-methoxymethoxy-3-(4-methoxymethoxyphenyl)-4-(2-propenyl)-3-propylchroman prepared as in Example 21 and ethyl 2-(4,4,5,5,5-pentafluoropentyl)-9-decenoate prepared separately, the same procedure as shown in Example 21 was repeated to give 11-[(3RS,4RS)-7-hydroxy-3-(4-hydroxyphenyl)-3-propylchroman-4-yl]-2-(4,4,5,5,5-pentafluoropentyl)undecanoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06552068B1 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-ce87cb004cac4825a48010588807c2e1 |
| Source note | uspto-grants-2003_04 |