Lithium hydroxide, monohydrate → HCID 18542421, compound

Participants

Reaction Steps

A mixture of the product from step (c) (1.33 g) and lithium hydroxide monohydrate (0.84 g) in methanol (120 ml) and water (25 ml) was heated at reflux for 2 hours, cooled and concentrated in vacuo. The residual aqueous solution was acidified with glacial acetic acid and extracted with ethyl acetate. The combined extracts were washed with water and brine, dried (MgSO4) and evaporated to give a cream solid. Yield 1.27 g.

Provenance & Evidence