Acetic Anhydride → 10-Acetoxy-5,5-dimethyl-8-(3-cyclopropyl-2-propyl)-5H-[1]benzopyrano[3,4-d]pyridine

HRID 126801Notes

Reaction equation

HRID 126801 reaction equation
[CH3:1][C:2]1([CH3:23])[C:18]2=[CH:19][CH:20]=[N:21][CH:22]=[C:17]2[C:5]2[C:6]([OH:16])=[CH:7][C:8]([CH:10]([CH2:12][CH:13]3[CH2:15][CH2:14]3)[CH3:11])=[CH:9][C:4]=2[O:3]1.[C:24](OC(=O)C)(=[O:26])[CH3:25]>N1C=CC=CC=1>[C:24]([O:16][C:6]1[C:5]2[C:17]3[C:18]([C:2]([CH3:1])([CH3:23])[O:3][C:4]=2[CH:9]=[C:8]([CH:10]([CH2:12][CH:13]2[CH2:14][CH2:15]2)[CH3:11])[CH:7]=1)=[CH:19][CH:20]=[N:21][CH:22]=3)(=[O:26])[CH3:25]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 202878695,5-dimethyl-10-hydroxy-8-(3-cyclopropyl-2-propyl)-5H-[1]benzopyrano[3,4-d]pyridine

Product 1

HCID 2028786710-Acetoxy-5,5-dimethyl-8-(3-cyclopropyl-2-propyl)-5H-[1]benzopyrano[3,4-d]pyridine

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

10-Acetoxy-5,5-dimethyl-8-(3-cyclopropyl-2-propyl)-5H-[1]benzopyrano[3,4-d]pyridine is prepared by reacting 5,5-dimethyl-10-hydroxy-8-(3-cyclopropyl-2-propyl)-5H-[1]benzopyrano[3,4-d]pyridine and acetic anhydride in the presence of pyridine according to the method of Example 12.

Sources & evidence

ORD record
ord-3d551d15ab504b158560132b9fe615cd
Source dataset
uspto-grants-1981_03
Patent number
US04254116

Reaction notes

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