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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1268059Generated: October 27, 2026

1-(4-Fluorophenyl)-2-methylpropan-1-ol → 1-(4-Fluorophenyl)-2-methylpropan-1-one

https://huagongshe.com/reaction/1268059

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Fluorophenyl)-2-methylpropan-1-olHCID 10419564—
ReactantJones' reagentHCID 131709961—
SolventAcetoneHCID 180—
Product1-(4-Fluorophenyl)-2-methylpropan-1-oneHCID 2782829—

Reaction Steps

To a solution of 1-(4-Fluoro-phenyl)-2-methyl-propan-1-ol (1.6 g) in acetone (10 mL) at 0° C. is added Jones reagent (20 mL) with stirring. After 10 minutes excess Jones reagent is destroyed by addition of isopropyl alcohol. Diethyl ether is added followed by anhydrous magnesium and the mixture is filtered and evaporated to give the product, a yellow oil (1.2 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06555561B2
Source datasetuspto-grants-2003_04
ORD IDord-fedeaa46d6d04783ad31564c564b7758
Source noteuspto-grants-2003_04