t-Butylaminodimethylsilylchloride → HCID 18544243, compound

Participants

Reaction Steps

(5,6-dimethoxy-3-phenyl-1H-inden-1-yl)lithium (1.24 g, 4.8 mmol) was dissolved in 20 mL of THF and added to a solution of N-(tert-butyl)-N-(1-chloro-1,1-dimethylsilyl)amine (1.035 g, 6.24 mmol) in 50 mL of THF over a 25 min period, with stirring continued for 20 h. The solution was then evaporated under reduced pressure and the residue was extracted with hexane (50 mL). After filtration, the solvent was removed under reduced pressure. To this residue, 30 mL of hexane was added and the flask was put aside into a freezer (−27° C.) for 2 days. After that time the crystallized solid was filtered off and the solvent was removed leaving 1.68 of the product as a yellow oil.

Provenance & Evidence