HCID 18542820, compound → HCID 18542765, compound

Participants

Reaction Steps

To a solution of 4-(1-t-butoxycarbonylpiperidin-4-yloxy)-3-methoxynitrobenzene (4.36 g) in methanol (60 ml) was added palladium on carbon (0.25 g) and the mixture was stirred under a hydrogen atmosphere at room temperature for 65 hours. The reaction mixture was filtered and the filtrate concentrated in vacuo. The residue was purified by chromatography on a silica gel column using hexane/ethyl acetate=1/1 as an eluant to give the desired compound (2.03 g, yield 51%) as a pale red oil.

Provenance & Evidence