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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 126820Generated: October 26, 2026

Dicyclohexylcarbodiimide → 5,5-Dimethyl-8-(3-methyl-2-octyl)-10-[4-(morpholino)butyryloxy]-5H-[1]benzopyrano[3,4-d]pyridine hydrochloride

https://huagongshe.com/reaction/126820

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDicyclohexylcarbodiimideHCID 10868—
Reactant4-Morpholin-4-Yl-Butyric Acid HydrochlorideHCID 12733746—
Reactant5,5-Dimethyl-10-hydroxy-8-(3-methyl-2-octyl)-5H-[1]benzopyrano[3,4-d]pyridineHCID 19781402—
Product5,5-Dimethyl-8-(3-methyl-2-octyl)-10-[4-(morpholino)butyryloxy]-5H-[1]benzopyrano[3,4-d]pyridine hydrochlorideHCID 20287838—

Reaction Steps

5,5-Dimethyl-8-(3-methyl-2-octyl)-10-[4-(morpholino)butyryloxy]-5H-[1]benzopyrano[3,4-d]pyridine hydrochloride is prepared according to the method of Example 29 by reacting equimolar quantities of 5,5-dimethyl-10-hydroxy-8-(3-methyl-2-octyl)-5H-[1]benzopyrano[3,4-d]pyridine and γ-morpholinobutyric acid hydrochloride in the presence of dicyclohexyl carbodiimide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04254116
Source datasetuspto-grants-1981_03
ORD IDord-b4a6fc6b4b4743cda912e4e6a675e77d
Source noteuspto-grants-1981_03