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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 126823Generated: October 26, 2026

Dicyclohexylcarbodiimide → 5,5-Dimethyl-8-(3-methyl-2-octyl)-10-[5-(piperidino)valeryloxy]-5H-[1]benzopyrano[3,4-d]pyridine hydrochloride

https://huagongshe.com/reaction/126823

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDicyclohexylcarbodiimideHCID 10868—
Reactant5,5-Dimethyl-10-hydroxy-8-(3-methyl-2-octyl)-5H-[1]benzopyrano[3,4-d]pyridineHCID 19781402—
Reactant5-(Piperidin-1-yl)pentanoic acid hydrochlorideHCID 54592761—
Product5,5-Dimethyl-8-(3-methyl-2-octyl)-10-[5-(piperidino)valeryloxy]-5H-[1]benzopyrano[3,4-d]pyridine hydrochlorideHCID 20287863—

Reaction Steps

5,5-Dimethyl-8-(3-methyl-2-octyl)-10-[5-(piperidino)valeryloxy]-5H-[1]benzopyrano[3,4-d]pyridine hydrochloride is prepared according to the method of Example 29 by reacting equimolar quantities of 5,5-dimethyl-10-hydroxy-8-(3-methyl-2-octyl)-5H-[1]benzopyrano[3,4-d]pyridine and δ-piperidinovaleric acid hydrochloride in the presence of dicyclohexyl carbodiimide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04254116
Source datasetuspto-grants-1981_03
ORD IDord-20d16a58919e430db8806fb8859ed869
Source noteuspto-grants-1981_03