HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisobutylaluminum hydride → (E)-3-(5'-chloro-2'-methoxy-biphenyl-4-yl)-but-2-en-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisobutylaluminum hydride | HCID 14487 | — |
| Reactant | (E)-Ethyl 3-(5'-chloro-2'-methoxy-biphenyl-4-yl)-but-2-enoate | HCID 22557579 | — |
| Product | (E)-3-(5'-chloro-2'-methoxy-biphenyl-4-yl)-but-2-en-1-ol | HCID 69799843 | — |
Reaction Steps
(E)-Ethyl 3-(5′-chloro-2′-methoxy-biphenyl-4-yl)-but-2-enoate (0.90 g, 2.72 mmol) was reduced with DIBAL-H by a procedure analogous to that described in example 52 b to give (E)-3-(5′-chloro-2′-methoxy-biphenyl-4-yl)-but-2-en-1-ol as a colourless oil; 0.785 g (100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06555577B1 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-934b1c0eec8b41f887ca648a47aed93a |
| Source note | uspto-grants-2003_04 |