HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl (2S)-2-ethoxy-3-(4-hydroxyphenyl)propanoate → (E)-(S)-Ethyl 3-{4-[3-(3'-Acetyl-biphenyl-4-yl)-but-2-enyloxy]-phenyl}-2-ethoxy-propionate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl (2S)-2-ethoxy-3-(4-hydroxyphenyl)propanoate | HCID 9816147 | — |
| Reactant | (E)-3-(3'-acetyl-biphenyl-4-yl)-but-2-en-1-ol | HCID 69799799 | — |
| Product | (E)-(S)-Ethyl 3-{4-[3-(3'-Acetyl-biphenyl-4-yl)-but-2-enyloxy]-phenyl}-2-ethoxy-propionate | HCID 86589953 | 65.8% |
Reaction Steps
The title compound (0.16 g, 65% yield) was prepared from (E)-3-(3′-acetyl-biphenyl-4-yl)-but-2-en-1-ol (0.133 g, 0.50 mmol) and (S)-ethyl 2-ethoxy-3-(4-hydroxyphenyl)-propionate (0.125 g, 0.525 mmol) by a procedure analogous to that described in example 52c.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06555577B1 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-a8ab9ca0c2184d1cab1062ff97e8a3c8 |
| Source note | uspto-grants-2003_04 |