HCID 22557642, compound → HCID 22557656, compound

HRID 1268292Notes

Reaction equation

HRID 1268292 reaction equation
[CH2:1]([C:9]1[CH:10]=[C:11]([CH2:23][OH:24])[CH:12]=[C:13]([CH2:15][CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH:14]=1)[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[Cr](Cl)([O-])(=O)=O.[NH+]1C=CC=CC=1>ClCCl>[CH2:1]([C:9]1[CH:10]=[C:11]([CH:12]=[C:13]([CH2:15][CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH:14]=1)[CH:23]=[O:24])[CH2:2][C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1

Participants

4

Reactant 2

HCID 22557642HCID 22557642, compoundHCID 178418287HCID 178418287, compound

Product 1

HCID 22557656HCID 22557656, compoundYield 64.6%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a solution of (3,5-diphenethyl-phenyl)-methanol (2.0 g, 6.4 mmol) in dry dichloromethane (30 mL) was added pyridinium chlorochromate (1.4 g, 6.4 mmol) and the mixture was stirred at room temperature for 16 h. The product was purified by flash chromatography using dichloromethane as solvent to give 1.3 g 3,5-diphenethyl-benzaldehyde.

Workup

  1. customThe product was purified by flash chromatography

Sources & evidence

ORD record
ord-68d04a8033154067861ebd9d8b298e85
Source dataset
uspto-grants-2003_04
Patent number
US06555577B1

Reaction notes

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