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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1268297Generated: November 3, 2026

2-Methylphenyl boronic acid → (E)-ethyl 3-(2'-methyl-biphenyl-4-yl)-but-2-enoate

https://huagongshe.com/reaction/1268297

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methylphenyl boronic acidHCID 2733267—
Reactant(E)-ethyl 3-(4-iodophenyl)-but-2-enoateHCID 11438459—
Product(E)-ethyl 3-(2'-methyl-biphenyl-4-yl)-but-2-enoateHCID 22557711—

Reaction Steps

The colourless solid, (E)-ethyl 3-(2′-methyl-biphenyl-4-yl)-but-2-enoate was prepared from (E)-ethyl 3-(4-iodophenyl)-but-2-enoate (example 91a) and ortho-tolyl boronic acid by a procedure analogous to that described in example 91b.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06555577B1
Source datasetuspto-grants-2003_04
ORD IDord-010ba04bd5af4877a4435be87c45490a
Source noteuspto-grants-2003_04