Ethyl trans-4-Bromocinnamate → HCID 22557655, compound

HRID 1268348Notes

Reaction equation

HRID 1268348 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5](/[CH:8]=[CH:9]/[C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:4][CH:3]=1.[Cl:15][C:16]1[CH:17]=[C:18](B(O)O)[CH:19]=[C:20]([Cl:22])[CH:21]=1>>[Cl:15][C:16]1[CH:17]=[C:18]([C:2]2[CH:7]=[CH:6][C:5](/[CH:8]=[CH:9]/[C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:4][CH:3]=2)[CH:19]=[C:20]([Cl:22])[CH:21]=1

Participants

3

Reactant 2

HCID 688115Ethyl trans-4-BromocinnamateHCID 27343313,5-Dichlorophenylboronic acid

Product 1

HCID 22557655HCID 22557655, compound

Procedure

The colourless solid (E)-ethyl 3-(3′,5′-dichloro-biphenyl-4-yl)-acrylate was prepared from (E)-ethyl 3-(4-bromo-phenyl)-acrylate (example 71a) and 3,5-dichlorobenzene boronic acid by a procedure analogous to that described in example 52a.

Sources & evidence

ORD record
ord-a3bf64680f9c4d5cb443e7082b7b16ce
Source dataset
uspto-grants-2003_04
Patent number
US06555577B1

Reaction notes

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