関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 1,5-Pentanediol | HCID 8105 | — |
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | gamma-Linolenoyl Chloride | HCID 11770936 | — |
| 触媒 | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 1-(z,z,z-Octadeca-6,9,12-trienoyloxy)-5-hydroxypentane | HCID 86758952 | — |
反応手順
z,z,z-Octadeca-6,9,12-trienoyl chloride (2 g) was added dropwise to a solution of 1,5-dihydroxypentane (3.5 g), triethylamine (0.94 ml) and 4-(N,N-dimethylamino)pyridine (0.2 g) in methylene chloride (50 ml) with stirring at 0° C. under nitrogen. On completion of reaction as evidenced by tic the reaction mixture was washed with dilute hydrochloric acid and water, dried and purified by column chromatography yielding 1-(z,z,z-octadeca-6,9,12-trienoyloxy)-5-hydroxypentane as a pale yellow oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US06555700B1 |
|---|
| 出典データセット | uspto-grants-2003_04 |
|---|
| ORD ID | ord-eedcf5fb534c4f6a8caf20bd555c7406 |
|---|
| 出典メモ | uspto-grants-2003_04 |
|---|
