Hydrogen Bromide → HCID 20288059, compound

Participants

Reaction Steps

A mixture of 55 parts of 5,6-dichloro-1,3-dihydro-1-(2-hydroxyethyl)-2-H-benzimidazol-2-one and 450 parts of a hydrobromic acid solution 48% in water is stirred and refluxed for 4 hours. The reaction mixture is poured onto ice-water and stirred to room temperature. The precipitated product is filtered off, stirred in water, filtered off again and dried, yielding 55.5 parts (87%) of 1-(2-bromoethyl)-5,6-dichloro-1,3-dihydro-2H-benzimidazol-2-one.

Provenance & Evidence