Aniline → 2-(4-Benzylaminopropoxyphenyl)-8-methylimidazo[1,2-a]pyridine

HRID 1268691Notes

Reaction equation

HRID 1268691 reaction equation
Cl[CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[N:13]=[C:14]3[C:19]([CH3:20])=[CH:18][CH:17]=[CH:16][N:15]3[CH:21]=2)=[CH:8][CH:7]=1.N[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1.[CH2:29]([NH:33]CCCC)CCC>>[CH2:29]([NH:33][CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[N:13]=[C:14]3[C:19]([CH3:20])=[CH:18][CH:17]=[CH:16][N:15]3[CH:21]=2)=[CH:8][CH:7]=1)[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1

Participants

4

Reactant 3

HCID 6115AnilineHCID 8148DibutylamineHCID 142014592-(4-Chloropropoxyphenyl)-8-methylimidazo[1,2-a]pyridine

Product 1

HCID 208031742-(4-Benzylaminopropoxyphenyl)-8-methylimidazo[1,2-a]pyridine

Procedure

This compound was prepared according to the procedure described in Example 1 of U.S. Pat. No. 4,727,145. using 2-(4-chloropropoxyphenyl)-8-methylimidazo[1,2-a]pyridine and aniline instead of 2-(4-chloropropoxyphenyl)-imidazo[1,2-a]pyridine and dibutylamine respectively.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-fd1249bcf2d14947a9be8288ce02fd56
Source dataset
uspto-grants-2007_04
Patent number
US07199117B2

Reaction notes

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