Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Acid → N-(1,3,4,9-tetrahydro-6-methoxy-2H-carbazol-2-yl)acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | Sodium Acetate | HCID 517045 | — |
| 반응물 | 4-Methoxyphenylhydrazine hydrochloride | HCID 2723904 | — |
| 반응물 | N-(3-oxocyclohexyl)acetamide | HCID 20529251 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | N-(1,3,4,9-tetrahydro-6-methoxy-2H-carbazol-2-yl)acetamide | HCID 20529230 | — |
반응 단계
A mixture of 0.05 mol of N-(3-oxocyclohexyl)acetamide, 0.05 mol of anhydrous NaOAc, 0.05 mol of 4-methoxyphenylhydrazine hydrochloride, and 155 ml of glacial HOAc was stirred for 1 hr at room temperature and then refluxed for 1 hr. The cooled reaction mixture was poured into H2O and the product triturated until solid. Filtration, drying, and recrystallization from ethanol gave the title compound, mp 191°-193°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04254134 |
| 출처 데이터셋 | uspto-grants-1981_03 |
| ORD ID | ord-aecb9e2823d0491580aecd77398a6053 |
| 출처 메모 | uspto-grants-1981_03 |