Sodium Carbonate → HCID 18446907, compound

Participants

Reaction Steps

To a solution of the product of Step 1 (15 g, 42.6 mmol) in dichloromethane (300 ml) at room temperature was added bromine (6.81 g, 2.38 ml, 46.5 mmol) followed by a saturated solution of sodium carbonate (150 ml). The mixture was stirred for 40 minutes before being separated and the organic layer washed successively with water and brine. The organic layer was then dried (magnesium sulphate) and concentrated in vacuo to give the title compound (18.1 g, 99%) as a brown viscous oil which was used without further purification; MS(AP+) m/e 431/433 [M+H]+.

Provenance & Evidence