Isobutylamine → HCID 18446645, compound

Participants

Reaction Steps

N-Isobutyl-2,3-bis[2-(isobutylamino)pyrimidin-4-yl]pyrazolo[1,5-a]pyridin-7-amine pyridine was prepared by treating 7-chloro-2,3-bis[2-(methylsulfinyl)pyrimidin-4-yl]pyrazolo[1,5-a]pyridine with isobutylamine as described in Example 7. 1H NMR, (400 MHz, CDCl3): δ 8.35 (d, 1H), 8.09 (d, 1H), 7.59 (d, 1H), 7.30 (d, 1H), 6.94 (bs, 1H), 6.57 (m, 1H), 6.16 (t, 1H), 6.00 (d, 1H), 5.26 (bs, 1H), 5.17 (bs, 1H), 3.25 (t, 3H), 3.18 (t, 3H), 2.00–2.15 (m, 1H), 1.85–1.95 (m, 2H), 0.90–1.10 (m, 18H); MS m/z 488 (M+1).

Provenance & Evidence