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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1269204Generated: November 1, 2026

2,2-Bis(4-fluorophenyl)acetic acid → N-{3-[1-(3-{[bis(4-fluorophenyl)acetyl]amino}propyl)-4-piperidinyl]-4-methoxyphenyl}butanamide

https://huagongshe.com/reaction/1269204

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2-Bis(4-fluorophenyl)acetic acidHCID 13511684—
ReactantN-{3-[1-(3-aminopropyl)4-piperidinyl]4-methoxyphenyl}butanamideHCID 21957241—
ProductN-{3-[1-(3-{[bis(4-fluorophenyl)acetyl]amino}propyl)-4-piperidinyl]-4-methoxyphenyl}butanamideHCID 21957260—

Reaction Steps

Example 26 was prepared from bis(4-fluorophenyl) acetic acid and N-{3-[1-(3-aminopropyl)-4-piperidinyl]-4-methoxyphenyl}butanamide according to the procedures described in Scheme 9: ESMS m/e: 564.4 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07199135B2
Source datasetuspto-grants-2007_04
ORD IDord-eb852bd8404e4ac6ae0e82478b74c15b
Source noteuspto-grants-2007_04