HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(p-Chlorophenyl)cyclobutanecarboxylic acid → 1-(4-chlorophenyl)-N-(3-{4-[3-(propionylamino)phenyl]-1-piperidinyl}propyl)cyclobutanecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(p-Chlorophenyl)cyclobutanecarboxylic acid | HCID 602761 | — |
| Reactant | N-{3-[1-(3-aminopropyl)4-piperidinyl]phenyl}propanamide | HCID 21957142 | — |
| Product | 1-(4-chlorophenyl)-N-(3-{4-[3-(propionylamino)phenyl]-1-piperidinyl}propyl)cyclobutanecarboxamide | HCID 21957192 | — |
Reaction Steps
Example 58 was prepared from 1-(4-chloro phenyl)cyclobutanecarboxylic acid and N-{3-[1-(3-aminopropyl)-4-piperidinyl]phenyl}propan amide according to the procedures described in Scheme 10: ESMS m/e: 482.3 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07199135B2 |
| Source dataset | uspto-grants-2007_04 |
| ORD ID | ord-b65c7d1f9fa0449db5442c54bef2ecf5 |
| Source note | uspto-grants-2007_04 |