HCID 70565362, compound → HCID 70566143, compound
Reaction equation
C([N:8]1[CH2:12][C@@H:11]([OH:13])[C@H:10]([NH:14][C:15](=[O:22])[C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH2:9]1)C1C=CC=CC=1>[Pd]>[OH:13][C@@H:11]1[CH2:12][NH:8][CH2:9][C@H:10]1[NH:14][C:15](=[O:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
A mixture of trans-N-(1-benzyl-4-hydroxy-3-pyrrolidinyl)benzamide and palladium-on-charcoal catalyst is hydrogenated at 60° C. for 4 hrs. to obtain the title compound.
Sources & evidence
- ORD record
- ord-6a6413c8a2124d8eaca4241f09ccf45c
- Source dataset
- uspto-grants-1981_03
- Patent number
- US04254135
Reaction notes
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