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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1269289Generated: November 1, 2026

1-(4-Chlorophenyl)cyclopentanecarboxylic acid → HCID 21957232, compound

https://huagongshe.com/reaction/1269289

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Chlorophenyl)cyclopentanecarboxylic acidHCID 97447—
ReactantN-{3-[1-(3-aminopropyl)4-piperidinyl]phenyl}cyclopropanecarboxamideHCID 21957166—
ProductHCID 21957232HCID 21957232—

Reaction Steps

Example 112 was prepared from 1-(4-chlorophenyl)cyclopentanecarboxylic acid and N-{3-[1-(3-aminopropyl)-4-piperidinyl]phenyl}cyclopropanecarboxamide according to the procedures described in Scheme 10: 1H NMR (400 MHz, CDCl3) δ 8.03–7.87 (br, 1H), 7.56–7.02 (m, 8H), 6.91–6.65 (br, 1H), 3.30–3.05 (m, 4H), 2.62–2.38 (m, 3H), 2.38–2.21 (m, 2H), 1.98–1.51 (m, 15H), 1.14–1.01 (m, 2H), 0.93–0.70 (m, 2H); ESMS m/e: 508.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07199135B2
Source datasetuspto-grants-2007_04
ORD IDord-8bfc431df705484ba8ca0d415c379950
Source noteuspto-grants-2007_04